Platelet Derived Growth Factors for Treatment of Wounds

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Platelet-rich plasma and platelet-derived lipid factors induce different and similar gene expression responses for selected genes related to wound healing in rat dermal wound environment

Although platelet-rich plasma (PRP) is the plasma fraction that contains higher levels of platelet-sequestered proteins such as growth factors and chemokines, it is also abundant in bioactive lipids whose role in wound healing has not been well characterized. This study provides a preliminary evaluation for the effect of the lipid component of PRP on selected genes related to wound healing. Spr...

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Determination of the Effect of Autologous Platelet Gel on Cutaneous Leishmaniasis Wounds Healing

Abstract Background and Objectives Platelet Gel (PG) is rich in growth factors with healing properties and is used in most surgeries to treat various types of tissue defects. In this study, the effect of autologous platelet gel (APG) was evaluated on healing of cutaneous leishmaniasis wounds.   Materials and Methods This randomized clinical trial was done on 15 patients with cutaneous leishm...

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Efficacy of Autologous Platelet-Rich Plasma (PRP) Activated By Thromboplastin-D on the Repair and Regeneration of Wounds in Dogs

Objective- To evaluate the effects of autologous platelet-rich plasma (PRP) on wound healing in dogs. Design- Experimental in-vivo study. Animals- 5 mix-breed male adult dogs. Procedures- Under general anesthesia, six 2 × 2-cm, full-thickness skin wounds were created on the back of dogs symmetrically. In each dog, three right side wounds were treated topically with 1.5 ml PRP jelly, whereas lef...

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تاریخ انتشار 2018